Table 3.
Comparison of outcomes among Peak EST groups for all patients treated
| Models: | Outcomes | P-value | |||
|---|---|---|---|---|---|
| Clinical Pregnancy | P-value | Conception | |||
| estimate (se) | estimate (se) | ||||
| Piece-wise linear Model** | Peak EST (peak EST < 14) | 0.32 (0.17) | 0.06 | 0.37 (0.16) | 0.022 |
| Peak EST (Peak EST > =14) | −0.94 (0.69) | 0.17 | −1.27 (0.68) | 0.06 | |
| Multiple logistic regression model *** | Adjusted OR(95%CI) | P-value | Adjusted OR(95%CI) | P-value | |
| Group 1 vs 3 | 0.44(0.16,1.21) | 0.11 | 0.61(0.23,1.58) | 0.31 | |
| Group 2 vs 3 | 0.77(0.52,1.14) | 0.2 | 0.69(0.48,0.99) | 0.046 | |
| ref, Group 3 | 1 | 1 | |||
| Group 4 vs 3 | 0.6(0.19,1.94) | 0.39 | 0.46(0.15,1.38) | 0.16 | |
**Multivariable piecewise linear model with change point at peak EST = 14
***: The adjusted OR (95%CI) were determined based on Multiple logistic regression model for the outcomes with GEE approach to account for the clustering of cycles for the same patient
For both models, the potential confounders adjusted for were age, dominant follicles, motile sperm count, and peak estrogen
Group 1: peak EST < 7 (mm); Group 2: peak EST: 7–10.4 (mm); peak EST: 10.5–13.9 (mm); Group 4: peak EST > =14 (mm)