Table 3.

Multivariate Cox regression analysis of factors predictive of prognosis in bladder cancer after radical cystectomy

Parameters	HR	95% CI	P	HR	95% CI	P	Parameters	HR
Multivariate Cox proportional analysis to metastasis
Age (< 70 vs. ≥70)	0.994	0.959	1.030	0.725	0.998	0.964	1.033	0.894
Gender (male vs. female)	0.825	0.354	1.923	0.655	0.745	0.288	1.928	0.544
BMI	0.972	0.867	1.088	0.618	0.957	0.854	1.073	0.450
Pathologic T stage	1.667	1.234	2.251	0.001	1.776	1.296	2.434	< 0.001
Lymph node involvement	1.727	0.895	3.335	0.103	1.816	0.942	3.501	0.075
Grade	0.640	0.078	5.249	0.678	0.549	0.065	4.629	0.582
De Ritis ratio (Low vs. high)	2.389	1.161	4.914	0.018
De Ritis ratio (Continuous)					1.582	1.129	2.219	0.008
Multivariate Cox proportional analysis of cancer-related death
Age (< 70 vs. ≥70)	0.996	0.959	1.035	0.834	1.000	0.964	1.038	0.988
Gender (male vs. female)	0.488	0.164	1.448	0.196	0.363	0.096	1.377	0.136
BMI	0.941	0.825	1.073	0.361	0.919	0.807	1.046	0.200
Pathologic T stage	1.841	1.297	2.612	0.001	1.933	1.342	2.784	< 0.001
Lymph node involvement	1.613	0.775	3.358	0.201	1.708	0.823	3.546	0.151
Grade	0.584	0.069	4.149	0.589	0.461	0.051	5.286	0.685
De Ritis ratio (Low vs. high)	2.755	1.214	6.249	0.015
De Ritis ratio (Continuous)					1.848	1.239	2.755	0.003
Multivariate Cox proportional analysis of overall death
Age (< 70 vs. ≥70)	0.999	0.963	1.037	0.956	1.004	0.969	1.041	0.807
Gender (male vs. female)	0.471	0.161	1.377	0.169	0.337	0.088	1.285	0.111
BMI	0.972	0.858	1.100	0.651	0.952	0.840	1.078	0.436
Pathologic T stage	1.921	1.368	2.698	< 0.001	2.017	1.415	2.876	< 0.001
Lymph node involvement	1.572	0.778	3.176	0.207	1.694	0.842	3.409	0.139
Grade	0.326	0.065	5.372	0.538	0.556	0.064	4.718	0.538
De Ritis ratio (Low vs. high)	2.761	1.257	6.067	0.011
De Ritis ratio (Continuous)					1.860	1.262	2.743	0.002

HR hazard ratio, CI confidence interval, BMI body mass index