Figure 6.

Anti-TNBC effect of PBL activated by TNBC TCL-loaded DC in vivo. Nude mice were immunized with PBL activated by 1×PBS (Control), negative DC (nonspecific), or DC loaded with different TNBC TCL plus MHSP65 (specific) and transplanted with corresponding TNBC cells near the right hind leg. Tumor volume was measured every 2 days. In each individual experiment, when the tumor volume reached to 3000 mm³ or on the day after tumor implantation was over 30, mice were sacrificed and tumor (A) MDA-MB-231 growth curves were plotted. (B) HCC1937 growth curves and tumors from mice. (C) MDA-MB-436 growth curves and tumors from mice. (D) HCC1187 growth curves and tumors from mice. * versus Control (1×PBS); ^# versus Nonspecific.