Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Jan 17;9:1563. doi: 10.3389/fphar.2018.01563

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2019 Gugliandolo, Fusco, D’Amico, Peditto, Oteri, Di Paola, Cuzzocrea and Navarra.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

BJe diminishes TNF-α and IL-1β production, MPO activity and plasma extravasation in LPS-induced periodontitis. A significant increase in TNF-α and IL-1β levels was found in gingivomucosal tissues from LPS-injected rats, as compared with the samples of sham-group (A,B), whereas treatment with BJe significantly decreased the generation of these cytokines (A,B). LPS significantly raised myeloperoxidase activity (C) compared with those found in sham-group, while BJe significantly reduced these enzymatic activity (C). BJe administration inhibited the increase in Evans blue extravasation induced by LPS (D). Data are mean ± SEM of 10 rats for each group). ^∗P < 0.05 vs sham group. °P < 0.05 vs LPS group.