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. 2019 Jan 17;9:1563. doi: 10.3389/fphar.2018.01563

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Copyright © 2019 Gugliandolo, Fusco, D’Amico, Peditto, Oteri, Di Paola, Cuzzocrea and Navarra.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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BJe modulates Bax and Bcl-2 expression. Western blot analyses performed on samples of gingivomucosal tissue from LPS-injected rats, compared to sham group, displayed an increase of Bax expression, that was found reduced in BJe-treated rats (A,C). Conversely, LPS decreased expression of Bcl-2 which raised in the rats treated with BJe (B,D). Densitometric analyses of blots were performed normalizing bands for β-actin. Blots in (A,B) are representative of three different gels. Data in (C,D) are means ± SEM of 10 rats for each group. ^∗P < 0.05 vs sham group. °P < 0.05 vs LPS group.