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Treatment with BIO-11006 aerosol inhibits MCh-induced mucin secretion from airway mucous cells. Average mucin content of airway sections from methacholine-challenged Ova/Ova mice pretreated with BIO-11006 (Bio6) or RNS aerosol as listed (n = 6, 2 airway sections from 3 mice), expressed as a percentage of average mucin content in saline challenged Ova/Ova mice (n = 10, 2 airway sections from 5 mice). *Statistically significant difference (P < 0.05).
