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SI (A–D), SV-FFM (E–H), and heart rate (I–L) as a function of scaled V̇o2 at baseline and 1 yr. CONT, sedentary (A, E, and I); CONT + ALG, sedentary plus Alagebrium (B, F, and J); EX, exercise training only (C, G, and K); EX + ALG, exercise training plus Alagebrium (D, H, and L). bpm, Beats/min Values are means ± SE.
