Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Jan 15;9:3167. doi: 10.3389/fimmu.2018.03167

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2019 Webb, Peckham, Radziszewska, Menon, Oliveri, Simpson, Deakin, Lee, Ciurtin, Butler, Wedderburn and Ioannou.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

PBMC TLR7 gene expression did not associate with X chromosome number or serum sex hormone. Pre- and post-pubertal healthy, transgender and TUS volunteers were included (n = 77), p-values represent the significance of the coefficient the variable shown as estimated by linear regression after correcting for the other variables in the model (X chromosome number, serum testosterone, and oestradiol). (A) PBMC TLR7 gene expression did not differ with X chromosome number (p = 0.512). (B,C) PBMC TLR 9 gene expression did not differ with X chromosome number (p = 0.318), but was negatively associated with serum testosterone concentration (p = 0.014). (D) After cells were pre-stimulated with IFNα, IFN score was significantly associated with serum oestradiol (p = 0.009, n = 58).