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. 2019 Jan 24;16(1):e1002737. doi: 10.1371/journal.pmed.1002737

Table 1. Parameters used to describe TB natural history and epidemiology in a Brazilian state.

Variable Definition Prisoner Ex-prisoner Community Source
β effective contact rate 17.0 (10–30) 8.08 (4–12) 8.08 (4–12) Calculated
μ birth/death rate 0.017 0.017 0.017 [25]
τ rate of progression from early latent to infectious 0.09 (0.005–0.1) 0.03 (0.005–0.1) 0.01 (0.005–0.1) Calibration
v rate of progression from late latent to infectious .0008 .0008 .0008 [26]
w rate of progression from early latent to late latent 0.2 0.2 0.2 [27]
α1 susceptibility to reinfection upon reexposure 0.21 0.21 0.21 [28]
α2 rate of reinfection from recovered to early latent 0.21 0.21 0.21 [28]
γ rate of relapse from recovered to infectious 0.01 0.01 0.01 [29]
d rate of diagnosis and treatment initiation 0.55 (0.5–1.0) 0.85 0.85 Calibration
q rate of incarceration N/A 0.0182 0.00196 Calculated
r rate of release from imprisonment 0.5 N/A N/A Estimated from SIGO

Parenthetical values are the ranges used in sensitivity and uncertainty analyses. All rates are annual.

Abbreviations: SIGO, Sistema Integrado de Gestão Operacional; TB, tuberculosis.