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. 2019 Jan 24;16(1):e1002730. doi: 10.1371/journal.pmed.1002730

Fig 6. Deep stroma score applied to the validation data set (DACHS cohort).

Fig 6

HRs with 95% CI in multivariable Cox models including cancer stage (I–IV), sex, and age for the deep stroma score. HR for OS, DSS, and RFS are plotted. The deep stroma score was stratified into high/low at the median of the training set. In this validation cohort, the deep stroma score was an independent prognostic factor over all stages and within stage III and stage IV tumors. The horizontal axis is scaled logarithmically (log 10). CI, confidence interval; DACHS, Darmkrebs: Chancen der Verhütung durch Screening; DSS, disease-specific survival; HR, hazard ratio; OS, overall survival; RFS, relapse-free survival.