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. 2019 Jan 24;14(1):e0210869. doi: 10.1371/journal.pone.0210869

Table 2. The list of TG derivatives with their experimental IC50 against DENV -2 NS2B/NS3pro.

Ligands R1 R2 R3 IC50 (μM)
1 (4-nitrophenyl)methanimine H H 1995
2 4-(iminomethyl)benzoic acid H H 1367
3 4-(iminomethyl)-2-methoxy-6-nitrophenol H H 28
4 3-methoxybenzenesulfinic acid H H 68
5 4-methoxybenzenesulfinic acid H H 55
6 3-methylbenzenesulfinic acid 3-methylbenzenesulfinic acid H 63
7 acetyl H H 151
8 butanoyl H H 57
9 isobutanoyl H H 3893
10 pentanoyl H H 1037
11 3-methylbutanoyl H H 80
12 hexanoyl H H 168
13 palmitoyl H H 132
14 benzoyl H H 370
15 acetyl H cyclopentyl 556
D0713 H 2-methylpyridine cyclopentyl 62
TG H H H 753
Panduratin A - - - 56