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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: J Immunol. 2018 Nov 19;202(1):194–206. doi: 10.4049/jimmunol.1800777

Figure 8. Rab1a activity in alveolar macrophages from patients with sepsis is associated with generation of IL-1β and IL-18 in the lung and respiratory dysfunction.

Figure 8.

(A) Representative blots showing the protein expression of GTP-Rab1a and total Rab1a in alveolar macrophages from 3 different control and septic patients. (B) Quantification of the levels of GTP-Rab1a and total Rab1a. n = 10 per group. *p<0.01, Student t test. (C, D) Correlation of Rab1a activity in alveolar macrophages from patients with the levels of IL-1β (C) or IL-18 (D) in the lung. (E, F) Correlation of Rab1a activity with the levels of PaO2/FiO2 (E), and APACHE II scores (F). n = 10 per group. The data were analyzed by linear regression analysis with a 95% confidence interval (C-F). Open circle, septic patients; closed triangle, control (non-septic patients).