Table 3. PICK1 Mutants binding to LKI.
PICK1 variant (LKI) | EC50 (nM) | Bmax (% of max) | N | ||
---|---|---|---|---|---|
Pick1 wt | 29 | ± | 4 | 56 ± 2 * | 7 |
PICK1 A87L | n.d | - | 3 | ||
Half label PICK1 A87L/WT | 123 | ± | 41 | 56 ± 2 * | 3 |
n.d: No detectable binding or that curves could not be reliably fitted to a saturable binding event.
n.d* Curve not fitted but for comparison an apparent Bmax is determined from the concentration endpoint.
* Comparable Bmax values.
§ Comparable Bmax values.
& Comparable Bmax values.