Table 2:
Patient demographics
| Characteristic | Number of subjects, n=31(%) |
|---|---|
| Age, median | 63 (range, 47–77) |
| Race/Ethnicity | |
| White | 26 (84%) |
| Black | 5 (16%) |
| Interval since diagnosis (median, days) | 156 (range, 22–3443) |
| Interval since last chemotherapy (median, days) | 10 (range, 0–38) |
| Tobacco abuse, former/current smokers | 10 (32%) |
| Median pack-years among smokers | 10 (range, 1–30) |
| Medical comorbidities | |
| None | 9 (29%) |
| One comorbidity | 12 (39%) |
| Two or more comorbidities | 10 (32%) |
| Type of medical comorbidities | |
| Hypertension | 18 (58%) |
| Obesity | 9 (29%) |
| Diabetes mellitus | 5 (16%) |
| Autoimmune disease | 1 |
| COPD | 0 |
| Non-chemotherapy immunosuppression | 2 (7%) |
| Primary disease site & histology | |
| Endometrium | 9 (29%) |
| Endometrioid | 3 |
| Clear cell/Uterine papillary serous | 1 |
| Sarcoma/Carcinosarcoma | 5 |
| Ovary | 19 (61%) |
| High grade serous | 17 |
| Low grade serous | 1 |
| arcinosarcoma | 1 |
| Cervix | 3 (10%) |
| Squamous cell carcinoma | 3 |
| Stage | |
| I | 7 (23%) |
| II | 2 (6%) |
| III | 18 (58%) |
| IV | 3 (10%) |
| Unstaged | 1 (3%) |
| Currently receiving chemotherapy | 31(100%) |
| Primary disease | 16 (52%) |
| Recurrent disease | 15 (48%) |
| Received prior therapy | |
| None | 16 (52%) |
| Chemotherapy only | 11 (35%) |
| Radiation only | 0 (0%) |
| Both | 4 (13%) |
| Received prior surgery | 28 (90%) |
| ANC on admission (median, days) | 160 (range, 0–1309) |
| ANC nadir (median, days) | 142 (range, 0–1065) |
*
COPD: chronic obstructive pulmonary disease; ANC: absolute neutrophil count