Table 4:
Low risk, n(%)(MASCC ≥ 21)n=18 | High risk, n(%)(MASCC < 21)n=13 | p-value | |
---|---|---|---|
Days of hospitalization, median, range | 4 (2–14 days) | 6 (3–10 days) | 0.123 |
Positive culture or documented infection | 10 (56%) | 7 (54%) | 0.925 |
Multiple positive cultures | 0 (0%) | 1 (8%) | 0.419 |
Positive blood or urine culture | 3 (17%) | 3 (23%) | 0.676 |
Antibiotic monotherapy at admission | 7 (39%) | 5 (38%) | 0.981 |
ICU admission | 0 (0%) | 2 (15%) | 0.168 |
Severe complication | 2 (11%) | 5 (38%) | 0.099 |
Multiple severe complications (≥2) | 1 (6%) | 3 (23%) | 0.284 |
Overall mortality | 0 (0%) | 0 (0%) | - |
Death due to neutropenic fever | 0 (0%) | 0 (0%) | - |
ANC on admission, median, range | 249 (20, 1309) | 150 (0, 990) | 0.418 |
ANC nadir, median, range | 249 (0, 1065) | 132 (0, 989) | 0.464 |
G-CSF given during hospitalization | 9 (50%) | 9 (69%) | 0.284 |
Neutropenic ≥7 days | 1/17 (6%) | 1/13 (8%) | 1.000 |
Chemotherapy delay | 6 (33%) | 7 (54%) | 0.253 |
Did not reach statistical significant given low sample size, but one may appreciate a clinically distinct difference in outcomes.
MASCC: Multinational Association of Supportive Care in Cancer; ICU: intensive care unit; ANC: absolute neutrophil count; G-CSF: granulocyte colony stimulating factor