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. 2019 Jan 24;9:710. doi: 10.1038/s41598-018-35979-z

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Gene Ontology (GO) analysis of genes conferring resistance to hypoculoside. Enrichment of GO terms among the top 336 genes conferring resistance (logFC value < −0.5 and P-value < 0.05) to hypoculoside was determined by using DAVID in combination with REVIGO. The three plots show the enrichment of GO terms in the following categories: (A) Biological Process, (B) Cellular Component and (C) Molecular Function. For each category, the semantic similarities between the non-redundant GO terms are represented as scatterplots in 2-dimensional space. Related GO terms cluster together in the plot. The p-value for the false discovery rates of each GO term is represented by the colour of the corresponding circle. The GO term frequency in the GO database is represented by the size of the corresponding circle.