Table 2.
The distribution of common MRI markers among the participants of the Taizhou Imaging Study.
| Findings | Entire study | Age, years | Gender | ||||
|---|---|---|---|---|---|---|---|
| 55–59 | 60–65 | P * | Males | Females | P * | ||
| N | 562 | 301 | 261 | 259 | 303 | ||
| Lacunes, n (%) | 150 (26.69) | 72 (23.92) | 78 (29.89) | 0.11 | 62 (23.94) | 88 (29.04) | 0.17 |
| WMH, n (%) | 60 (10.68) | 22 (7.31) | 38 (14.56) | 0.006 | 26 (10.04) | 34 (11.22) | 0.65 |
| Periventricular | 60 (10.68) | 22 (7.31) | 38 (14.56) | 0.006 | 26 (10.04) | 34 (11.22) | 0.65 |
| Deep | 49 (8.72) | 16 (5.32) | 33 (12.64) | 0.002 | 19 (7.34) | 30 (9.90) | 0.28 |
| CMB, n (%) | 104 (18.51) | 43 (14.29) | 61 (23.37) | 0.006 | 38 (14.67) | 66 (21.78) | 0.03 |
| Brain stem | 10 (1.78) | 5 (1.66) | 5 (1.92) | 0.82 | 5 (1.93) | 5 (1.65) | 0.80 |
| Basal ganglia | 50 (8.90) | 24 (7.97) | 26 (9.96) | 0.41 | 19 (7.34) | 31 (10.23) | 0.23 |
| Cortical | 69 (12.28) | 27 (8.97) | 42 (16.09) | 0.01 | 25 (9.65) | 44 (14.52) | 0.08 |
| PVS, n (%) | 156 (27.76) | 80 (26.58) | 76 (29.12) | 0.50 | 73 (28.19) | 83 (27.39) | 0.83 |
| Number of SVD markers, n (%) | |||||||
| 0 | 298 (53.02) | 169 (56.15) | 129 (49.43) | 0.009 | 143 (55.21) | 155 (51.16) | 0.19 |
| 1 | 149 (26.51) | 86 (28.57) | 63 (24.14) | 69 (26.64) | 80 (26.40) | ||
| 2 | 47 (8.36) | 17 (5.65) | 30 (11.49) | 21 (8.11) | 26 (8.58) | ||
| 3 | 45 (8.01) | 19 (6.31) | 26 (9.96) | 16 (6.18) | 29 (9.57) | ||
| 4 | 23 (4.09) | 10 (3.32) | 13 (4.98) | 10 (3.86) | 13 (4.29) | ||
| ICAS, n (%) | 72 (12.81) | 43 (14.29) | 29 (11.11) | 0.26 | 28 (10.81) | 44 (14.52) | 0.19 |
| ICA | 5 (0.89) | 4 (1.33) | 1 (0.38) | 0.23 | 4 (1.54) | 1 (0.33) | 0.13 |
| MCA | 45 (8.01) | 27 (8.97) | 18 (6.90) | 0.37 | 15 (5.79) | 30 (9.90) | 0.07 |
| ACA | 5 (0.89) | 1 (0.33) | 4 (1.53) | 0.13 | 1 (0.39) | 4 (1.32) | 0.24 |
| BA | 10 (1.78) | 6 (1.99) | 4 (1.53) | 0.68 | 2 (0.77) | 8 (2.64) | 0.10 |
| VA | 18 (3.20) | 8 (2.66) | 10 (3.83) | 0.43 | 8 (3.09) | 10 (3.30) | 0.89 |
| BGMF, median (IQR), %# | 37.8 (34.0, 40.2) | 38.3 (34.9,40.5) | 37.3 (33.4, 39.8) | 0.02 | 35.7 (30.7, 37.7) | 39.7 (37.7, 41.0) | <0.0001 |
| BPF, median (IQR), %# | 73.3 (71.1, 75.8) | 73.5 (71.3, 75.6) | 73.1 (70.8, 76.1) | 0.26 | 72.8 (70.0, 76.5) | 73.6 (71.7, 75.4) | 0.02 |
WMH, white matter hyperintensity; CMB, cerebral microbleeds; PVS, perivascular space; SVD, small vessel diseases; ICAS, intracranial arterial stenosis; BGMF, brain gray matter fraction; BPF, brain parenchymal fraction; IQR, interquartile range.
#Numbers of missing data were 31.
*The P-values were obtained using Kruskal-Wallis test for continuous variables with skewed distribution, and using chi-square test for categorical variables.