Table 4.
Associations of cognitive function assessed by MMSE with the common MRI findings among the participants of the Taizhou Imaging Study.
| MRI markers | MMSE score (log-transformed) | |
|---|---|---|
| β (SE)# | P # | |
| Lacunes | 0.02 (0.02) | 0.43 |
| WMH | 0.03 (0.03) | 0.35 |
| CMB | 0.003 (0.02) | 0.90 |
| PVS | 0.03 (0.02) | 0.12 |
| Number of SVD markers | ||
| 1–2 vs 0 | 0.02 (0.02) | 0.28 |
| 3–4 vs 0 | 0.002 (0.03) | 0.92 |
| ICAS | 0.007 (0.03) | 0.80 |
| BGMF, % | 0.003 (0.002) | 0.15 |
| BPF, % | 0.002 (0.002) | 0.41 |
WMH, white matter hyperintensity; CMB, cerebral microbleeds; PVS, perivascular space; SVD, small vessel diseases; ICAS, intracranial arterial stenosis; BGMF, brain gray matter fraction; BPF, brain parenchymal fraction.
#Adjusted for age (per year), sex (male versus female), BMI (per kg/m2), education (per year), smoking (ever versus never), alcohol drinking (ever versus never), hypertension (yes versus no), diabetes (yes versus no), and hyperlipidemia (yes versus no).