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. 2019 Jan 24;9:444. doi: 10.1038/s41598-018-36914-y

Table 1.

Impact of myocardial infarction on general characteristics, relative heart weight LV mass and infarct size in rats submitted to myocardial infarction fed a standard diet (AMI) or a high fat diet (HFD-AMI) and rats fed a control diet and with SHAM operation (CT).

Parameter CT AMI HFD-AMI
Body weight (g) 396.2 ± 10.8 394.8 ± 9.7 470.2 ± 13.8***†††
Adiposity (%) 6.5 ± 0.5 4.9 ± 0.5 11.1 ± 0.9***†††
Plasma Leptin levels (ng/ml) 2.2 ± 0.2 2.5 ± 0.4 20.3 ± 4.3***†††
HOMA 3.2 ± 0.5 2.5 ± 0.4 8.6 ± 1.2***†††
Plasma Glucose levels (mg/dl) 111.8 ± 1.1 114.7 ± 4.4 130.0 ± 4.9*
Plasma TC levels (mg/dl) 71.8 ± 3.9 75.6 ± 4.5 83.3 ± 5.9
Plasma TG levels (mg/dl) 92.7 ± 8.7 84.6 ± 10.1 135.9 ± 10.5**††
SBP (mmHg) 127.72 ± 2.7 132.6 ± 1.3 131.0 ± 0.01.7
Heart relative weight (g/cm tibia) 0.229 ± 0.01 0.253 ± 0.008* 0.271 ± 0.003***
LV mass (g) 0.287 ± 0.061 0.420 ± 0.015*** 0.477 ± 0.02***
Infarct size/LV mass (%) 18.1 ± 2.9 20.7 ± 1.6

HOMA: Homeostatic model assessment; TC: total cholesterol; TG: triglycerides. SBP: Systolic blood pressure; LV: Left ventricle. Data are expressed as mean ± SEM. of 8–10 animals. *P < 0.05; **P < 0.01; ***P < 0.001 vs control group. P < 0.05; ††P < 0.01; †††P < 0.001 vs AMI group.