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. 2019 Jan 24;9:487. doi: 10.1038/s41598-018-37422-9

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Distribution of 64 ARGs in the genomes of 70 different MDR P. aeruginosa strains. Protein sequences encoded by the 64 ARGs (far left column) were aligned against all protein sequences deduced from genomes of 70 different MDR P. aeruginosa strains (top line), with several thresholds of similarity (S) and length coverage (L); (S > 95% and L > 95%, S > 90% and L > 90%, S > 80% and L > 80%, S > 70% and L > 70%). Seventy MDR strains are listed in Table S4 with detailed information. Presence of 64 genes in each genome is indicated with color-coded square boxes. The heat map was constructed by applying the color that satisfied the highest threshold. The blue-colored and red-colored genes were designated as gene group 1 (GG1) and gene group 2 (GG2), respectively.