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. 2019 Jan 24;9:589. doi: 10.1038/s41598-018-36968-y

Table 3.

Interactive effect (OR(95%CI)) of maternal colds and depressive symptoms on the occurrence of CHD.

Depressionb N Controls Cases Model 1c Model 2d
Colds a
0 0 458(24.86) 358(29.15) 100(16.29) 1 1
0 1 505(27.42) 310(25.24) 195(31.76) 2.25(1.69–3.00) 1.94(1.37–2.74)
1 0 502(27.25) 339(27.61) 163(26.55) 1.72(1.29–2.30) 1.48(1.04–2.09)
1 1 377(20.47) 221(18.00) 156(25.41) 2.53(1.87–3.42) 2.72(1.87–3.93)
Colds with fever a
0 0 920(49.95) 674(54.89) 246(40.07) 1 1
0 1 859(46.63) 518(42.18) 341(55.54) 1.80(1.48–2.20) 1.88(1.47–2.40)
1 0 40(2.17) 23(1.87) 17(2.77) 2.03(1.06–3.85) 1.79(0.80–4.02)
1 1 23(1.25) 13(1.06) 10(1.63) 2.11(0.91–4.87) 1.75(0.65–4.73)
Colds without fever a
0 0 496(26.93) 380(30.94) 116(18.89) 1 1
0 1 528(28.66) 323(26.3) 205(33.39) 2.08(1.58–2.73) 1.81(1.30–2.52)
1 0 464(25.19) 317(25.81) 147(23.94) 1.52(1.14–2.02) 1.30(0.92–1.84)
1 1 354(19.22) 208(16.94) 146(23.78) 2.30(1.71–3.09) 2.54(1.76–3.65)

a0 = No and 1 = Yes.

b0 = lower score and 1 = higher score.

cNo other factors were adjusted.

dAdjusted for Model 1 and maternal age, education, economic status, maternal smoking, drinking, taking folic acid, taking medicine, pregnancy reaction, abnormal prenatal examination, negative life events, chronic disease, natural abortion history, family history of CHD, baby gender.