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. 2019 Jan 24;9:589. doi: 10.1038/s41598-018-36968-y

Table 4.

Multiplication models and additive models of maternal colds and depressive symptoms on the occurrence of CHD.

Interactions Model 1d Model 2e
Multiplication model Depression * colds 2.08(1.58–2.74) 2.04(1.47–2.83)
Additive model RERIa 0.59(−0.36–1.54) 0.55(−0.54–1.64)
APb 0.19(−0.09–0.47) 0.19(−0.15–0.53)
Sc 1.40(0.79–2.46) 1.40(0.70–2.81)
Multiplication model Depression *colds with fever 1.55(0.67–3.55) 1.31(0.49–3.52)
Additive model RERI −0.72(−2.9–1.46) −0.91(−3.18–1.35)
AP −0.34(−1.61–0.92) −0.52(−2.23–1.18)
S 0.61(0.11–3.39) 0.45(0.04–5.18)
Multiplication model Depression *colds without fever 2.19(1.65–2.92) 2.21(1.57–3.09)
Additive model RERI 0.78(−0.15–1.71) 0.83(−0.25–1.9)
AP 0.26(−0.01–0.53) 0.28(−0.03–0.59)
S 1.64(0.87–3.09) 1.75(0.8–3.85)

aThe relative excess risk due to interaction.

bThe attributable proportion.

cThe synergy index.

dNo other factors were adjusted.

eAdjusted for Model 1 and maternal age, education, economic status, maternal smoking, drinking, taking folic acid, taking medicine, pregnancy reaction, abnormal prenatal examination, negative life events, chronic disease, natural abortion history, family history of CHD, baby gender.