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. 2019 Jan 24;9:589. doi: 10.1038/s41598-018-36968-y

Table 5.

Sensitivity analysis of interactive effect (OR(95%CI)) between maternal colds and depressive symptoms on CHD.

Coldsa Depressionb N Controls Cases Model 1c Model 2d
Wealth index
Poor 0 0 96(23.94) 70(29.41) 26(15.95) 1 1
0 1 79(19.70) 45(18.91) 34(20.86) 2.03(1.08–3.83) 1.64(0.71–3.78)
1 0 140(34.91) 84(35.29) 56(34.36) 1.80(1.02–3.15) 1.70(0.81–3.55)
1 1 86(21.45) 39(16.39) 47(28.83) 3.25(1.75–6.02) 2.96(1.30–6.73)
Moderate 0 0 265(24.27) 206(27.95) 59(16.62) 1 1
0 1 368(33.70) 222(30.12) 146(41.13) 2.30(1.61–3.28) 1.82(1.17–2.83)
1 0 258(23.63) 185(25.1) 73(20.56) 1.38(0.93–2.05) 1.24(0.76–2.02)
1 1 201(18.41) 124(16.82) 77(21.69) 2.17(1.45–3.25) 2.63(1.59–4.37)
Rich 0 0 97(27.79) 82(32.41) 15(15.63) 1 1
0 1 58(16.62) 43(17.00) 15(15.63) 1.91(0.85–4.27) 1.89(0.75–4.76)
1 0 104(29.80) 70(27.67) 34(35.42) 2.66(1.34–5.27) 2.40(1.10–5.21)
1 1 90(25.79) 58(22.92) 32(33.33) 3.02(1.50–6.07) 3.43(1.55–7.58)
Taking folic acid
No 0 0 66(25.00) 47(31.13) 19(16.81) 1 1
0 1 50(18.94) 34(22.52) 16(14.16) 1.16(0.52–2.59) 1.01(0.34–3.01)
1 0 76(28.79) 41(27.15) 35(30.97) 2.11(1.05–4.24) 3.22(1.25–8.32)
1 1 72(27.27) 29(19.21) 43(38.05) 3.67(1.80–7.47) 4.22(1.53–11.64)
Yes 0 0 392(24.84) 311(28.88) 81(16.17) 1 1
0 1 455(28.83) 276(25.63) 179(35.73) 2.49(1.83–3.39) 1.97(1.36–2.85)
1 0 426(27.00) 298(27.67) 128(25.55) 1.65(1.20–2.27) 1.31(0.89–1.92)
1 1 305(19.33) 192(17.83) 113(22.55) 2.26(1.61–3.17) 2.45(1.63–3.68)
Baby gender
Male 0 0 243(24.60) 195(30.14) 48(14.08) 1 1
0 1 275(27.83) 164(25.35) 111(32.55) 2.75(1.85–4.09) 2.30(1.42–3.72)
1 0 261(26.42) 172(26.58) 89(26.1) 2.10(1.40–3.16) 1.82(1.12–2.96)
1 1 209(21.15) 116(17.93) 93(27.27) 3.26(2.15–4.94) 3.50(2.11–5.82)
Female 0 0 215(25.18) 163(28.06) 52(19.05) 1 1
0 1 230(26.93) 146(25.13) 84(30.77) 1.80(1.20–2.72) 1.65(0.99–2.76)
1 0 241(28.22) 167(28.74) 74(27.11) 1.39(0.92–2.1) 1.24(0.74–2.08)
1 1 168(19.67) 105(18.07) 63(23.08) 1.88(1.21–2.92) 2.16(1.24–3.76)

a0 = No and 1 = Yes.

b0 = lower score and 1 = higher score.

cNo other factors were adjusted.

dAdjusted for Model 1 and maternal age, education, maternal smoking, drinking, taking medicine, pregnancy reaction, abnormal prenatal examination, negative life events, chronic disease, natural abortion history, family history of CHD and economic status/taking folic acid/baby gender.