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. 2019 Jan 24;9:589. doi: 10.1038/s41598-018-36968-y

Table 6.

Sensitivity analysis of multiplication models and additive models between maternal colds and depressive symptoms on CHD.

Interactions Model 1d Mode 2e
Wealth index
Poor Multiplication model Depression * colds 2.07(1.28–3.35) 2.01(1.06–3.83)
Additive model RERIa 0.42(−1.36–2.19) 0.62(−1.47–2.70)
APb 0.13(−0.39–0.65) 0.21(−0.43–0.85)
Sc 1.23(0.50–3.03) 1.46(0.37–5.77)
Moderate Multiplication model Depression * colds 1.37(1.01–1.88) 1.96(1.30–2.96)
Additive model RERIa −0.51(−1.48–0.46) 0.57(−0.60–1.75)
APb −0.23(−0.7–0.24) 0.22(−0.18–0.62)
Sc 0.7(0.36–1.33) 1.54(0.59–4)
Rich Multiplication model Depression * colds 1.68(1.01–2.82) 1.99(1.10–3.6)
Additive model RERIa −0.55(−2.75–1.66) 0.14(−2.34–2.62)
APb −0.18(−0.93–0.57) 0.04(−0.68–0.76)
Sc 0.79(0.32–1.94) 1.06(0.36–3.08)
Taking folic acid
No Multiplication model Depression * colds 2.58(1.48–4.50) 2.43(1.10–5.39)
Additive model RERIa 1.39(−0.71–3.49) 0.99(−2.61–4.58)
APb 0.38(−0.08–0.84) 0.23(−0.51–0.98)
Sc 2.09(0.57–7.63) 1.44(0.37–5.66)
Yes Multiplication model Depression * colds 1.34(1.03–1.74) 1.77(1.28–2.45)
Additive model RERIa −0.88(−1.79–0.03) 0.17(−0.77–1.11)
APb −0.39(−0.82–0.04) 0.07(−0.30–0.45)
Sc 0.59(0.36–0.97) 1.14(0.56–2.31)
Baby gender
Male Multiplication model Depression * colds 1.72(1.26–2.34) 2.13(1.43–3.17)
Additive model RERIa −0.59(−1.93–0.74) 0.38(−1.16–1.93)
APb −0.18(−0.61–0.24) 0.11(−0.31–0.53)
Sc 0.79(0.48–1.31) 1.18(0.60–2.34)
Female Multiplication model Depression * colds 1.36(0.96–1.93) 1.69(1.08–2.64)
Additive model RERIa −0.31(−1.26–0.63) 0.27(−0.87–1.41)
APb −0.17(−0.68–0.35) 0.12(−0.38–0.63)
Sc 0.74(0.31–1.75) 1.30(0.39–4.30)

aThe relative excess risk due to interaction.

bThe attributable proportion.

cThe synergy index.

dNo other factors were adjusted.

eAdjusted for Model 1 and maternal age, education, maternal smoking, drinking, taking medicine, pregnancy reaction, abnormal prenatal examination, negative life events, chronic disease, natural abortion history, family history of CHD and economic status/taking folic acid/baby gender.