Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Jan 24;9:665. doi: 10.1038/s41598-018-36878-z

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

S100B inhibitor decreases 5-FU-induced expression of RAGE and NFκB NLS in enteric neurons and RAGE and NFκB p65 protein expression in the jejunum. (A) Jejunal immunofluorescence images demonstrate HuC/D (red) and RAGE (green) expression and their co-localization (Merge, yellow). Nuclei were stained with DAPI. Scale bar, 50 µm. (B) RAGE protein expression was evaluated by Western Blot. Bars represent mean ± SEM for 6 tissue samples in each group. ^#P < 0.01 versus control group, *P < 0.01 versus 5-FU group. (C) Immunofluorescence images from the jejunum represent HuC/D (red) and NFκB NLS (green) and their co-localization (Merge, yellow). Nuclei were stained with DAPI. Scale bar, 50 µm. (D) NFκB p65 protein expression was evaluated by Western Blot. Bars represent mean ± SEM for 6 tissue samples in each group. ^#P < 0.01 versus control group, *P < 0.01 versus 5-FU group. One-way ANOVA followed by Bonferroni.