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. 2019 Jan 24;10:323. doi: 10.1038/s41467-018-08152-3

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — XBP1 gene signature is strongly associated with prostate cancer prognosis. Kaplan–Meier graphs demonstrating a significant association between high expression of the XBP1 signature (red line) and shorter disease-free survival in the TCGA (a), MSKCC (b) and GSE94767 (c) patient datasets. Kaplan–Meier curves showing significant association of elevated XBP1 gene signature expression (red line) with shorter biochemical recurrence (BCR) free survival in TCGA (d), GSE70768 (e), and GSE70769 (f) cohorts of PCa patients. The log-rank test P values are shown