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. 2019 Jan 24;9:615. doi: 10.1038/s41598-018-36349-5

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Expression heatmap of the six ginsenoside biosynthesis candidate PgCYP genes in different aged roots and tissues. The six ginsenoside biosynthesis candidate PgCYP genes newly identified in this study are bolded. All published genes involved in ginsenosides biosynthesis, CYP, AS, CAS, SE, SS, UGT, FPS and DS, were used as controls. (A) Heatmap of the genes expressed in the roots of differently-aged plants. One of the six ginsenoside biosynthesis candidate PgCYP genes did not express in the roots. (B) Heatmap of the genes expressed in the tissues of a four-year-old plant.