Table 2.
The PgCYP genes that are significantly correlated with the variation of ginsenoside contents in the four-year-old roots of 42 farmers’ cultivars and also have mutations that are significantly associated with ginsenoside contents.
| Gene | Position nucleotide mutation | Mutation type | Effect % (P-value) | ||||
|---|---|---|---|---|---|---|---|
| Rg1 | Re | Rc | Rb2 | TS | |||
| PgCYP149 | 70_CT_C | ORF shift | |||||
| 73_C_CGTGTGA AAATAAAAGAA ACCCAGAACCCA TTAAAGCACCAG | ORF shift | 52.0 (5.50E-04) | 30.7 (9.38E-05) | ||||
| PgCYP218 | 667_A_G | S | 69.08 (2.90E-05) | ||||
| 681_T_C | NS | 63.81 (3.60E-05) | |||||
| PgCYP222 | 647_T_G | NS | 62.7 (1.63E-04) | ||||
| PgCYP305 | 1214_A_AAT | ORF shift | 69.9 (1.19E-04) | ||||
| PgCYP341 | 140_G_A | Not in ORF | 73.1 (8.69E-04) | ||||
| PgCYP385 | 468_G_A | NS | 52.6 (8.08E-04) | ||||
Mono-ginsenosides, Rg1, Re, Rc and Rb2; Total ginosenosides, TS; S, synonymous substitution; NS, non-synonymous substitution; ORF, open-reading frame.