Figure 5.

Hierarchical clustering analysis of differential expression at transcripts and exons level. (a) Log₂ expression ratio between CPT treated and untreated cells for the 5666 transcripts detected as differentially expressed in at least one of the two experimental groups, i.e. WT2 and A-T2. (b) ENSEMBL transcripts distribution as function of transcripts’ length. Dashed lines indicate the three groups of transcripts, from left to right, ≤175 nts (7872 transcripts), (ii) >175 nts ≥1300 nts (122719 transcripts) ad (iii) >1300 nts (67307 transcripts). (c) Transcripts showing a Pearson correlation below 0.2, in all replicates, comparing CPT treated vs untreated WT2 and A-T2 neurons.