Table 5.

Per-protocol analysis of the primary outcome for participants with >80% compliance

	Calcium (n/N [%])	Placebo (n/N [%])	Risk ratio	95% CI	p value
Compliance >80% from randomisation up to the last PPV
Pre-eclampsia*	20/98 (20%)	33/100 (33%)	0·62 (0·38–1·00)	..	0·045
Compliance >80% from last PPV to the 20-week visit
Pre-eclampsia†	30/144 (21%)	47/149 (32%)	0·66 (0·44–0·98)	..	0·037
Compliance >80% from randomisation up to the last PPV and compliance >80% from last PPV to the 20-week visit
Pre-eclampsia	14/69 (20%)	23/72 (32%)	0·64 (0·36–1·13)	..	0·116

PPV=prepregnancy visit.

^*98 in the calcium group, because one participant was not eligible and one was lost to follow-up.

^†144 in the calcium group because one participant was not eligible.