FIG 4.

Histopathological observations in dogs impacted by vaccination. Shown are one section each of representative samples for all tissue samples (cerebrum, cerebellum, brainstem, lung, and liver) at a ×20 magnification. The histological sections were similar for CTR and WCA-vaccinated dogs, having minimal lesions attributed to a normal immune response, while the nonvaccinated ADJ and RCA-vaccinated groups had similar lesions, which are more severe than those observed in dogs belonging to the CTR and WCA groups.