Scheme 2.
Synthesis of compounds 57–64. a) Acetic anhydride, K2CO3, MeCN (to 57–61); b) cyclopropanecarbonyl chloride, DIPEA, DCM (to 62); c) methyl chloroformate, DIPEA, DCM (to 63); d) MsCl, DIPEA, DCM (to 64).
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