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. 2018 Dec 18;8(1):351–362. doi: 10.1002/cam4.1812

Figure 7.

Figure 7

Down‐regulation of CCNG1 reduced tumor metastasis in vivo. A, H&E staining of lung metastasis of shCCNG1‐A2780 cell line and its control. B, Nude mice injected with shCCNG1‐A2780 cell line developed fewer lung metastatic foci than its control (< 0.0001). C, CCNG1 was regulated by P53mt via induction of Notch3 expression, which ultimately promotes both HGSOC tumor cell metastasis and cisplatin resistance