Table 2.
Summary of Reviewed Studies.
| First Author (Year) | Design | Sample |
|---|---|---|
| Bevans (2016) | Longitudinal; T1 = before HSCT, T2 = DC, T3 = 6 weeks after DC | CGs = 21; NCs = 20 |
| Cohen (2005) | Cross-sectional | CGs (daughter, localized CA) = 39; CGs (daughter, advanced CA) = 41 |
| Fancourt (2016) | Longitudinal; T1 = pre-INT, T2 = post-INT; saliva collection at 7:00 p.m. (pre-INT), 8:15 p.m. (post-INT) | CGs (current) = 72; CGs (bereaved) = 66; patients = 55 |
| Goodfellow (2003) | Longitudinal; T1 = pre-INT, T2 = immediately post-INT, T3 = 20-min post-INT | CGs (INT) = 21; CGs (control) = 21 |
| Khalaila (2014) | Cross-sectional | CGs (CA) = 68; CGs (non-CA) = 42 |
| Laudenslager (2015) | Longitudinal; T1 = baseline, T2 = 4 weeks, T3 = 12 weeks; saliva collection upon awakening, 30-min postawakening | CGs (INT) = 74; CGs (control) = 74 |
| Lengacher (2012) | Longitudinal; T1 = baseline, T2 = 1 week, T3 = 3 weeks, T4 = 6 weeks; saliva collection at 2 time points (pre-INT, post-INT) | CGs = 23; patients = 24 |
| Lucini (2008) | Cross-sectional; saliva collected at 7:30 a.m., 10:30 p.m. | CGs = 58; NCs = 60 |
| Lutz Stehl (2008) | Cross-sectional | CGs (parent) = 19 |
| Miller (2002) | Cross-sectional; saliva collected 1,4, 9, 11, and 13 hr after awakening | CGs = 25; NCs = 25 |
| Miller (2008) | Cross-sectional; saliva collected upon awakening and 0.5, 1, 4, 9, and 14 hr after awakening | CGs = 11; NCs = 10 |
| Miller (2014) | Longitudinal; T1 = baseline, T2–T4 = 2, 4, and 8 months; saliva collected upon awakening and 0.5, 1, 4, 9, and 14 hr after awakening | CGs = 33; NCs = 47 |
| Nightingale (2017) | Longitudinal; T1 = initiation of RT, T2 = 5 weeks into RT; saliva collected upon awakening and at 9:00 p.m. | CGs = 32 |
| Pinar (2015) | Longitudinal; T1 = baseline, T2 = Day 7 | CGs (INT) = 22; CGs (control) = 22 |
| Rohleder (2009) | Longitudinal; T1 = before RT, T2 = after RT, T3 = 6 weeks after RT, T4 = 4 months after RT | CGs = 18; NCs = 19 |
| Sherwood (2016) | Longitudinal; T1 = baseline (within 3 months of diagnosis), T2–T4 = 4, 8, and 12 months | CGs = 134 |
| Thomas (2012) | Cross-sectional; saliva collected upon awakening, 30 min and 8-hr postawakening, and at bedtime | CGs (female) = 19; NCs (female) = 26 |
| Walsh (2007) | Longitudinal; T1 = pre-INT, T2 = post-INT; saliva collection at 2 time points (pre-INT, post-INT) | CGs = 69 |
Note. CA = cancer; CG = caregiver; DC = discharge; HSCT = hematopoietic stem cell transplantation; INT = intervention; NC = noncaregiver; RT = radiotherapy; T = time point.