Table 5.
Functional Capacity, Symptoms, and Quality of Life at Baseline and 6 and 12 Months After Cardiopulmonary Rehabilitation in Veterans With HF and COPD, Combined, by Mortality Group.
Variable | Time Point | Wald χ2 | p Value | ||||
---|---|---|---|---|---|---|---|
Baseline (Mean ± SD) | 6 Months (Mean ± SD) | 12 Months (Mean ± SD) | Groupa | Group × Timeb | Groupa | Group × Timeb | |
Functional capacity | |||||||
6MWD (m) | 2.36 | 1.13 | .12 | .29 | |||
Total | 354.69 ± 117.39 | 343.17 ± 113.89 | 314.29 ± 131.29 | ||||
Alive at 12 months | 367.28 ± 113.48 | 349.62 ± 131.62 | 314.29 ± 131.29 | ||||
Dead at 12 months | 225.70 ± 73.13 | 192.63 ± 110.74 | — | ||||
Total steps/24 hr | 1.37 | 0.89 | .24 | .34 | |||
Total | 5,337.27 ± 3,053.33 | 5,244.92 ± 3,120.10 | 5,327.00 ± 3,324.02 | ||||
Alive at 12 months | 5,551.47 ± 3,077.57 | 5,327.79 ± 3,154.98 | 5,327.00 ± 3,324.02 | ||||
Dead at 12 months | 3,141.74 ± 1,699.58 | 3,558.53 ± 611.42 | — | ||||
Symptoms | |||||||
COPD Dyspnea Scale | 3.99 | 0.76 | .04 | .38 | |||
Total | 3.02 ± 1.40 | 2.69 ± 1.36 | 2.85 ± 1.58 | ||||
Alive at 12 months | 2.90 ± 1.38 | 2.67 ± 1.32 | 2.85 ± 1.58 | ||||
Dead at 12 months | 4.25 ± 0.93 | 3.17 ± 2.27 | — | ||||
Quality of life | |||||||
SF-36 V, PCS | 0.29 | 0.54 | .59 | .46 | |||
Total | 31.96 ± 8.19 | 32.83 ± 10.27 | 32.02 ± 10.99 | ||||
Alive at 12 months | 32.63 ± 7.95 | 33.35 ± 10.06 | 32.02 ± 10.99 | ||||
Dead at 12 months | 25.12 ± 7.84 | 19.96 ± 7.56 | — | ||||
SF-36 V, MCS | 5.92 | 11.84 | .02 | .001 | |||
Total | 48.84 ± 11.81 | 51.47 ± 11.67 | 50.04 ± 11.53 | ||||
Alive at 12 months | 49.11 ± 12.06 | 51.20 ± 11.81 | 50.04 ± 11.53 | ||||
Dead at 12 months | 46.06 ± 9.08 | 58.05 ± 3.46 | — | ||||
SF-36 V, physical function | 5.04 | 1.08 | .025 | .29 | |||
Total | 38.63 ± 20.68 | 43.53 ± 23.55 | 41.76 ± 25.00 | ||||
Alive at 12 months | 40.27 ± 20.70 | 44.67 ± 22.90 | 41.76 ± 25.00 | ||||
Dead at 12 months | 21.85 ± 11.31 | 15.00 ± 25.98 | — | ||||
SF-36 V, general health | 0.33 | 2.33 | .57 | .12 | |||
Total | 46.69 ± 18.41 | 48.67 ± 20.88 | 48.89 ± 20.58 | ||||
Alive at 12 months | 48.44 ± 17.85 | 50.16 ± 19.72 | 48.89 ± 20.58 | ||||
Dead at 12 months | 28.50 ± 14.82 | 11.67 ± 16.07 | — | ||||
Cardiopulmonary function | |||||||
FEV1 | 4.65 | 2.23 | .03 | .14 | |||
Total | 39.85 ± 19.20 | 41.82 ± 22.35 | 44.62 ± 20.87 | ||||
Alive at 12 months | 40.83 ± 19.58 | 42.49 ± 22.49 | 44.62 ± 20.87 | ||||
Dead at 12 months | 29.75 ± 11.18 | 25.50 ± 3.53 | — | ||||
NT-proBNP | 1.15 | 2.79 | .28 | .09 | |||
Total | 1,086.28 ± 2,013.60 | 727.10 ± 2,013.60 | 708.86 ± 1,124.69 | ||||
Alive at 12 months | 985.93 ± 1,913.75 | 722.55 ± 968.84 | 708.86 ± 1,124.69 | ||||
Dead at 12 months | 2,114.88 ± 2,800.81 | 863.50 ± 775.70 | — | ||||
Self-efficacy | |||||||
Self-efficacy exercise | 0.30 | 0.14 | .59 | .71 | |||
Total | 6.44 ± 2.33 | 5.63 ± 2.45 | 5.28 ± 2.89 | ||||
Alive at 12 months | 6.61 ± 2.24 | 5.72 ± 2.42 | 5.28 ± 2.89 | ||||
Dead at 12 months | 4.67 ± 2.62 | 3.22 ± 2.14 | — | ||||
Self-efficacy walking | 4.02 | 0.45 | .05 | .83 | |||
Total | 2.82 ± 2.42 | 3.82 ± 3.08 | 3.20 ± 2.92 | ||||
Alive at 12 months | 2.96 ± 2.48 | 3.92 ± 3.09 | 3.20 ± 2.92 | ||||
Dead at 12 months | 1.38 ± .92 | 1.33 ± 1.53 | — |
Note. Total N = 90; alive at 12 months = 82; dead at 12 months = 8. 6MWD = 6-min walk distance; COPD = chronic obstructive pulmonary disease; HF = heart failure; FEV1 = forced expiratory volume in 1 s; MCS = mental component score; NT-proBNP = N-terminal pro-brain natriuretic peptide; PCS = physical component score; SF-36 V = Short-Form 36–Veterans version.
aGroup differences between those who were alive at 12 months compared with those who had died by 12 months. bDead and alive Trajectory × Time.