Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Apr 15;25(7):1037–1044. doi: 10.1177/1933719118770552

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

PMC Copyright notice

Figure 3. — Histological and immunohistochemical analysis. Histological studies showed that (A) no pathologic changes were detected in control animals at 24 hours postischemia. B, Vascular congestion, edema, and severe intraparenchymal hemorrhage were observed in ischemia and reperfusion (IR) group at 24 hours postischemia. C, Normal histology was observed in the control group at 2 weeks postischemia. D, Increased inflammatory cell infiltration (the majority are leucocytes and macrophages) and epithelial cell proliferation determined at 2 weeks postischemia. Vascular congestion (vc), hemorrhage (h), edema (e), hyperplasia (hp), and inflammatory cells infiltration (*). Immunohistochemical studies showed (E) caspase 3 expression in the control group at 24 hours after ischemia. F, Increased caspase-3 expression was observed in epithelial (dashed arrow in magnified view) and stromal (arrow) cells of IR group at 24 hours after ischemia. G, Caspase-3 expression in the control group 2 weeks after ischemia. H, Caspase-3 expression gradually decreased and comparable levels with the control group were seen at 2 weeks after ischemia.