Table 1. Molecular weights (MWs) and critical micelle concentrations (CMCs) of novel agents (A-MNGs), MNG-10,10 and a conventional detergent (DDM), and hydrodynamic radii (Rh; n = 4–5) of their micelles at room temperature.
Detergent | MW a | CMC (μM) | CMC (wt%) | R h b (nm) |
MNG-10,10 | 1005.20 | ∼10 | 0.001 | 9.8 ± 0.2 |
MNG-9,11 | 1005.20 | ∼8 | 0.0008 | 8.3 ± 1.0 |
MNG-8,12 | 1005.20 | ∼8 | 0.0008 | 6.0 ± 0.2 |
MNG-6,14 | 1005.20 | ∼6 | 0.0006 | 3.8 ± 0.1 |
MNG-4,16 | 1005.20 | ∼4 | 0.0004 | 3.5 ± 0.2 |
MNG-2,18 | 1005.20 | ∼2 | 0.0002 | 4.1 ± 0.2 |
MNG-0,20 | 1005.20 | ∼2 | 0.0002 | 3.9 ± 0.1 |
DDM | 510.62 | 170 | 0.0087 | 3.4 ± 0.0 |
aMolecular weight of detergents.
bHydrodynamic radius of detergents measured at 1.0 wt% by dynamic light scattering experiments.