Table 1. Interdependence between clinical and laboratory findings and outcome for patients with Crimean-Congo hemorrhagic fever, Kosovo, 2013–2016*.
Finding | χ2 | p value |
---|---|---|
Significant interdependence with outcome, with Yates correction | ||
Clinical findings | ||
Fasciculations | 14.0 | <0.001 |
Coma | 13.2 | <0.001 |
Somnolence | 6.5 | 0.010 |
Hemoperitoneum | 10.4 | 0.001 |
Bleeding gums | 8.8 | 0.003 |
Hematemesis | 7.7 | 0.005 |
Melena | 5.7 | 0.017 |
Petechiae | 5.7 | 0.017 |
Ecchymoses | 5.5 | 0.019 |
Jaundice | 6.2 | 0.013 |
Diarrhea | 5.7 | 0.017 |
Hiccup | 4.0 | 0.046 |
Laboratory findings | ||
Viral load >1 × 108.5/mL | 18.5 | <0.001 |
LDH >2,200 U/mL | 9.56 | 0.002 |
Leukocytes >7,700/µL |
7.4 |
0.006 |
No interdependence with outcome, without Yates correction | ||
Clinical findings | ||
Vertigo | 2.26 | 0.133 |
Hypertension | 1.97 | 0.160 |
Anorexia | 1.72 | 0.189 |
Nausea | 1.60 | 0.205 |
Epistaxis | 0.90 | 0.340 |
Vomiting | 0.74 | 0.388 |
Joint pain | 0.74 | 0.388 |
Sweating | 0.23 | 0.631 |
Headache | 0.13 | 0.722 |
Conjunctivitis | 0.13 | 0.722 |
Muscular pain | 0.08 | 0.773 |
Abdominal pain | 0.05 | 0.830 |
Hypotension | 0.03 | 0.864 |
Bradycardia | <0.01 | 0.968 |
Laboratory findings | ||
ALT >168 U/mL | 1.54 | 0.215 |
AST >147 U/mL | 1.47 | 0.225 |
CK >1,037 U/mL |
0.79 |
0.373 |
Nonsignificant trend toward interdependence with outcome | ||
Platelets <50,000/µL | 3.68 | 0.055 |
With Yates correction | 3.63 | 0.057 |
*ALT, alanine aminotransferase; AST, aspartate aminotransferase; CK, creatine kinase; LDH, lactate dehydrogenase.