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. 2019 Feb;25(2):220–228. doi: 10.3201/eid2502.171974

Table 1. Sensitivity and specificity of microscopy and F1RDT for the diagnosis of human plague cases, Madagascar*.

Clinical form Microscopy, 1998–2001
F1RDT, 2002–2008
Sensitivity Specificity Sensitivity Specificity
Bubonic 34% (31%–38%) 96% (95%–97%) 100% (99%–100%) 60% (58%–62%)
Pneumonic
53% (34%–71%)
94% (84%–98%)

100% (90%–100%)
45% (37%–52%)
Total 35% (32%–39%) 96% (95%–97%) 100% (99%–100%) 59% (57%–61%)

*Values in parentheses are ranges. Bacteriological culture was used as a reference test. F1RDT, Yersinia pestis antigen fraction 1 rapid diagnostic test.