Fig. 3.

The effects of intracerebroventricular (ICV) combined treatments with lower (A) and medium (B) doses of vitamin B₁₂ and diclofenac on muscle pain behavior induced by intramuscular (IM) injection of formalin. Diclofenac and vitamin B₁₂ were ICV administered 10 and 5 min before IM injection of formalin, respectively. Data are the means ± SEM obtained from six rats.  * p < 0.05 compared to normal saline treated group. ** p < 0.05 compared to normal saline, diclofenac (12.50 µg) and vitamin B₁₂ (2.50 µg) treated groups