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. 2018 Dec 15;9(4):329–335. doi: 10.30466/vrf.2018.33104

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© 2018 Urmia University.

This is an open-access article distributed under the terms of the Creative Commons Attribution-noncommercial 4.0 International License, (https://creativecommons.org/licenses/by-nc/4.0/) which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.

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Fig. 4 — The effects of intracerebroventricular (ICV) injection of naloxone on vitamin B₁₂ (A)- and diclofenac(B)-induced antinociception. Naloxone and diclofenac were ICV injected 10 min before induction of pain. Vitamin B₁₂ was ICV administered 5 min before intramuscular injection of formalin. Data are the means ± SEM obtained from six rats. * p < 0.05 compared to vitamin B₁₂ (10.00 µg) treated group. ^†p < 0.05 compared to diclofenac (25.00 µg) treated group.