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. 2019 Jan 24;19:104. doi: 10.1186/s12885-018-5225-5

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — miR-342-3p suppresses NPC cell growth and invasion in vitro. a Real-time PCR analysis of miR-342-3p levels in NPC cells transfected with the miR-342-3p-expressing plasmid or vector. b Analysis of proliferation by MTT assay in NPC cells transfected with the miR-342-3p-expressing plasmid or vector. c Colony formation assay performed in NPC cells transfected with the miR-342-3p-expressing plasmid or vector. Left, representative images of colonies. d Transwell invasion assay. Ectopic expression of miR-342-3p significantly decreased the invasion of C666 and CN2 cells, compared to control cells. Column: mean of three independent experiments performed in three replicates. Error bar: SD. ^*P < 0.05