Table 2.
Logistic regression model of factors with potential predictive value
Parameter | PRDVT | Distant VTE | All VTE | |||
---|---|---|---|---|---|---|
Odds Ratio (95%CI) |
P value | Odds Ratio (95%CI) |
P value | Odds Ratio (95%CI) |
P value | |
Age on insertion | 0.97 (0.92, 1.02) | 0.270 | 1.02 (0.97, 1.08) | 0.393 | 1.00 (0.96, 1.04) | 0.971 |
Female | 0.29 (0.54, 1.59) | 0.155 | 2.50 (0.75, 8.33) | 0.135 | 1.81 (0.65, 5.04) | 0.254 |
Primary cancer type | ||||||
Breast | N/A | N/A | 1.18 (0.04, 31.75) | 0.922 | 2.76 (0.169, 45.00) | 0.746 |
Colorectal | N/A | N/A | 0.84 (0.03, 26.54) | 0.923 | 1.07 (0.09, 13.65) | 0.959 |
Pancreas | N/A | N/A | 0.82 (0.02, 42.66) | 0.920 | 2.82 (0.137, 58) | 0.502 |
Intention to treatment | ||||||
Adjuvant | 1.16 (0.25, 5.42) | 0.851 | N/A | N/A | 1.43 (0.33, 6.198) | 0.629 |
Palliative | 1.33 (0.12, 15.32) | 0.187 | N/A | N/A | 4.62 (0.57, 37.56) | 0.153 |
Ongoing antiplatelet or anticoagulation therapy | 1.31 (0.21, 8.22) | 0.777 | 2.91 (0.34, 24.76) | 0.329 | 1.30 (0.30, 5.69) | 0.730 |
Previous VTE event | 1.28 (0.17, 9.77) | 0.814 | 0.27 (0.02, 2.91) | 0.277 | 0.77 (0.16, 3.61) | 0.740 |
Smoking | 3.90 (1.09, 13.98) | 0.036* | 0.29 (0.05, 1.66) | 0.166 | 1.61 (0.59, 4.40) | 0.351 |
Pervious risk factor for VTE | 0.40 (0.07, 2.42) | 0.315 | 0.66 (0.12, 3.36) | 0.612 | 0.54 (0.15, 1.95) | 0.348 |
Fluropyrimidine containing chemotherapy | 5.87 (0.69, 50.22) | 0.106 | 6.80 (0.21, 224.50) | 0.283 | 10.06 (1.6, 63.05) | 0.014* |
BMI ≥ 30 | 1.11 (1.01, 1.23) | 0.026* | 1.12 (1.00, 1.23) | 0.033* | 1.13 (1.05, 1.22) | 0.001* |
WBC count | 0.86 (0.69, 1.08) | 0.202 | 1.08 (0.95, 1.23) | 0.218 | 1.01 (0.91, 1.12) | 0.865 |
Platelet count | 1.01 (1.00, 1.01) | 0.103 | 1.00 (1.00, 1.01) | 0.245 | 1.00 (1.00, 1.01) | 0.034* |
Prior PICC line in last 6 months | 0.74 (0.08, 7.14) | 0.791 | 3.97 (0.80, 19.78) | 0.092 | 2.16 (0.58, 8.03) | 0.252 |
DVT deep vein thrombosis, PICC peripherally inserted central catheter, PRDVT, PICC related DVT, VTE vascular thromboembolism, CI confidence interval, WBC white blood cells, BMI body mass index, N/A not applicable
*= P < 0.05 statistically significant