Table 3.
Gene | Ensembl | FPKM | TPM | Top variant | MAF | Beta | SE | P |
---|---|---|---|---|---|---|---|---|
APOL3 | ENSBTAG00000040244 | 0.934 | 1.166 | rs433710540 | 0.101 | 0.128 | 0.0315 | 4.84 × 10−5 |
CSF2RB | ENSBTAG00000009064 | 61.888 | 80.081 | rs384734208 | 0.439 | 0.428 | 0.0401 | 1.33 × 10−26 |
EIF3D | ENSBTAG00000001988 | 9.139 | 11.461 | rs110614216 | 0.353 | − 0.072 | 0.0138 | 1.66 × 10−7 |
FOXRED2 | ENSBTAG00000000015 | 0.142 | 0.179 | rs385243246 | 0.176 | 0.036 | 0.0133 | 6.52 × 10−3 |
IFT27 | ENSBTAG00000026657 | 0.904 | 1.107 | rs110654851 | 0.440 | 0.046 | 0.0103 | 8.01 × 10−6 |
IL2RB | ENSBTAG00000016345 | 0.285 | 0.359 | rs43436480 | 0.364 | 0.058 | 0.0184 | 1.61 × 10−3 |
MPST | ENSBTAG00000030648 | 1.564 | 1.957 | rs109488885 | 0.314 | − 0.053 | 0.0144 | 2.40 × 10−4 |
MYH9 | ENSBTAG00000010402 | 14.448 | 17.497 | rs377857213 | 0.034 | 0.280 | 0.0715 | 9.07 × 10−5 |
NCF4 | ENSBTAG00000007531 | 0.406 | 0.513 | rs209273109 | 0.443 | 0.137 | 0.0168 | 4.30 × 10−16 |
TST | ENSBTAG00000030650 | 2.131 | 2.662 | rs109922126 | 0.073 | − 0.152 | 0.0313 | 1.19 × 10−6 |
TXN2 | ENSBTAG00000000014 | 4.345 | 5.653 | rs109450151 | 0.454 | − 0.080 | 0.0116 | 5.85 × 10−12 |
Genes with FPKM values less than 0.1 are not shown. Gene symbols are from VGNC and Ensembl. Beta is the effect size of the minor allele on gene expression, measured in VST-transformed units. Three genes have eQTL which exceed the genome-wide significance threshold 5 ×10−8 [60]