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. 2019 Jan 18;9:3166. doi: 10.3389/fimmu.2018.03166

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Copyright © 2019 Twisselmann, Bartsch, Pagel, Wieg, Hartz, Ehlers and Härtel.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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IgG Fc glycosylation in preterm infants is dependent on gestational age. (A) IgG with agalactosylated Fc glycans were significantly increased, whereas (B) IgG with terminally galactosylated Fc glycans were unchanged and IgG with (C) sialylated and (D) bisecting Fc glycans were significantly decreased in preterm infants born < 28 weeks of gestational age. Term infants served as controls (mean ± SD, Kruskal-Wallis test). ^*p < 0.05, ^**p < 0.01, ^***p < 0.0001.