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. 2019 Jan 3;12(2):337–349. doi: 10.1111/eva.12744

Figure 4.

Figure 4

Siglecs bind to the gonococcal porin in a human‐specific manner. Purified PorinB.1A from 15253 (a) and PorinB.1B from F62 (b) were immobilized, and binding of human and chimpanzee Siglec‐Fc proteins was detected with anti‐human IgG‐HRP (Fc specific). Data were corrected for unspecific binding to BSA and represented as mean ± SD, n = 3, p‐values for PorinB.1A and PorinB.1B, respectively, Siglec‐5 p = 0.002/0.009, Siglec‐9 p < 0.001/<0.001, Siglec‐11 p = 0.023/0.006, Siglec‐14 p < 0.001/=0.001, and Siglec‐16 p < 0.001/=0.006)