Table 2.
Method | nSNP | β (FNK (95%CI)) | p-Value (FNK BMD) | β (LS BMD(95%CI)) | p-Value (LS BMD) |
---|---|---|---|---|---|
Fixed effects meta analysis (simple SE) | 116 | −0.072 (−0.111, −0.033) | 0.0002 | −0.072 (−0.115, −0.029) | 0.002 |
Fixed effects meta analysis (delta method) | 116 | −0.071 (−0.110, −0.032) | 0.0003 | −0.070 (−0.115, −0.025) | 0.002 |
Random effects meta analysis (delta method) | 116 | −0.066 (−0.111, −0.021) | 0.004 | −0.067 (−0.116, −0.018) | 0.008 |
Maximum likelihood | 116 | −0.072 (−0.111, −0.033) | 0.0003 | −0.071 (−0.116, −0.026) | 0.002 |
MR Egger | 116 | −0.139 (−0.276, −0.002) | 0.0497 | −0.091 (−0.244, 0.062) | 0.245 |
Weighted median | 116 | −0.098 (−0.161, −0.035) | 0.002 | −0.084 (−0.155, −0.013) | 0.020 |
Inverse variance weighted | 116 | −0.072 (−0.115, −0.030) | 0.001 | −0.072 (−0.121, −0.023) | 0.004 |