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. Author manuscript; available in PMC: 2019 Jan 25.
Published in final edited form as: Bone. 2018 Sep 18;117:91–97. doi: 10.1016/j.bone.2018.09.015

Table 2.

Results from different MR methods for FNK BMD and LS BMD.

Method nSNP β (FNK (95%CI)) p-Value (FNK BMD) β (LS BMD(95%CI)) p-Value (LS BMD)
Fixed effects meta analysis (simple SE) 116 −0.072 (−0.111, −0.033) 0.0002 −0.072 (−0.115, −0.029) 0.002
Fixed effects meta analysis (delta method) 116 −0.071 (−0.110, −0.032) 0.0003 −0.070 (−0.115, −0.025) 0.002
Random effects meta analysis (delta method) 116 −0.066 (−0.111, −0.021) 0.004 −0.067 (−0.116, −0.018) 0.008
Maximum likelihood 116 −0.072 (−0.111, −0.033) 0.0003 −0.071 (−0.116, −0.026) 0.002
MR Egger 116 −0.139 (−0.276, −0.002) 0.0497 −0.091 (−0.244, 0.062) 0.245
Weighted median 116 −0.098 (−0.161, −0.035) 0.002 −0.084 (−0.155, −0.013) 0.020
Inverse variance weighted 116 −0.072 (−0.115, −0.030) 0.001 −0.072 (−0.121, −0.023) 0.004