Table 3.

Timeline of Assessments and Self-report Measures

	Assessments
Construct & Measure	Daily	Baseline	3-months	6-months	12-months	18-months
Aim 1
AET Adherence
AdhereTech Smart Pill Bottle	X
Medication taking Behavior
Revised Medication Adherence Rating Scale		X	X	X	X	X
Aim 2
Subjective Reports of Symptoms & Symptom Interference
Menopause Specific Quality of Life Questionnaire		X	X	X	X	X
Brief Pain Inventory- Short Form		X	X	X	X	X
Brief Pain Inventory-Short Form, Pain Severity Subscale		X	X	X	X	X
Arthritis Impact Measurement Scale-II		X	X	X	X	X
Insomnia Severity Index		X	X	X	X	X
Patient Reported Outcomes Information System Fatigue Scale		X	X	X	X	X
Patient Reported Outcomes Information System Depression Scale		X	X	X	X	X
Patient Reported Outcomes Information System Anxiety Scale		X	X	X	X	X
Objective Measures of Physical Functioning and Symptom Interference
6-minute walk test		X	X	X	X	X
Get up and go test		X	X	X	X	X
Grip Strength		X	X	X	X	X
਀
Aim 3
Barriers to Taking AET
Barriers to taking medication		X	X	X	X	X
Treatment Interference
Treatment Burden Questionnaire		X	X	X	X	X
Beliefs about Medication
Beliefs about Medicines Questionnaire		X	X	X	X	X
Self-efficacy for managing symptoms and taking AET
Self-Efficacy for managing symptoms		X	X	X	X	X
Self-Efficacy for Appropriate Medication Use Scale		X	X	X	X	X
Aim 4
Cost-Effectiveness
5-level EuroQol-5 Dimensions (EQ-5D-5L) health questionnaire		X	X	X	X	X
Other Measures
Treatment Credibility and Satisfaction
Treatment Credibility Questionnaire			X
Satisfaction with Therapy and Therapist Scale				X
Potential Covariates
Participant Characteristics
Medical Characteristics (e.g., change in AET type, dosage)		X	X	X	X	X
Demographic Characteristics		X
Self-Report Disease Burden Scale		X	X	X	X	X
Treatments for comorbidities		X
Rapid Estimate of Adult Literacy in Medicine		X
Newest Vital Sign		X
Chronic Life Stressors Scale		X	X	X	X	X
Economic Pressures/Concerns		X	X	X	X	X