Table 2.
Changes in Physiological Parameters before and after Peroral Endoscopic Myotomy
| Characteristic | Preoperative values | Postoperative values | p-value |
|---|---|---|---|
| EndoFLIP | |||
| DI30mL, mm2/mm Hg | 3.5±2.6 | 11.4±6.0 | <0.001 |
| DI40mL, mm2/mm Hg | 3.3±2.7 | 12.5±7.4 | <0.001 |
| CSA30mL, mm2 | 71.7±67.1 | 173.7±96.1 | <0.001 |
| CSA40mL, mm2 | 94.4±78.4 | 263.6±124.8 | <0.001 |
| HRM, mm Hg | |||
| LES pressure | 30.3±18.1 | 13.5±9.4 | <0.001 |
| IRP | 27.8±27.1 | 11.4±6.8 | <0.001 |
| Questionnaire | |||
| Eckardt score | 6.4±2.7 | 1.3±1.1 | <0.001 |
| Development of reflux symptoms | 9 | 37 | <0.001 |
| Endoscopy | |||
| Reflux esophagitis | 3 | 24 | <0.001 |
| LA:A | 1 | 7 | |
| LA:B | 2 | 13 | |
| LA:C | 0 | 4 | |
| 24-hour pH monitoring | |||
| Incidence of GERD | 9 | 27 | <0.001 |
Data are presented as mean±SD or number.
DI, distensibility Index; CSA, cross-sectional area; HRM, high-resolution manometry; LES, lower esophageal sphincter; IRP, integrated relaxation pressure; LA, Los Angeles; GERD, gastroesophageal reflux disease.