Table 3.
Factors Associated with Incomplete Response to Peroral Endoscopic Myotomy
| Postoperative ES ≥3 (n=10) | Postoperative ES <3 (n=42) | p-value | |
|---|---|---|---|
| Male sex | 5 (18.5) | 22 (81.5) | 0.89 |
| Age, yr | 44.5±17.6 | 42.1±14.8 | 0.65 |
| BMI, kg/m2 | 22.4±3.5 | 22.4±3.8 | 0.44 |
| Follow-up duration, day | 209.9±121.0 | 307.6±275.6 | 0.58 |
| Duration of disease, yr | 4.5±3.1 | 6.0±8.6 | 0.58 |
| Maximal diameter of esophagus, mm | 30.5±9.1 | 45.3±69.7 | 0.53 |
| Myotomy length, mm | 83.0±12.5 | 92.9±17.9 | 0.10 |
| DI30mL, mm2/mm Hg | 8.53±5.67 | 14.00±8.36 | 0.07 |
| DI40mL, mm2/mm Hg | 9.51±4.00 | 14.17±8.16 | 0.10 |
| CSA30mL, mm2 | 167.00±86.01 | 205.52±116.68 | 0.35 |
| CSA40mL mm2 | 256.67±80.66 | 284.49±137.08 | 0.56 |
| Esophageal shape | 0.31 | ||
| Sigmoid | 0 | 4 | |
| Non-sigmoid | 10 | 38 | |
| Full myotomy | 5 | 33 | 0.07 |
| Selective myotomy | 5 | 9 | |
| Post-DI30 or DI40 <7 | 6 | 5 | 0.001 |
| Post-DI30 or DI40 ≥7 | 4 | 37 | |
| Decrease in LES pressure | 4 | 32 | 0.03 |
| Increase in LES pressure | 6 | 10 | |
| Decrease in IRP | 4 | 33 | 0.02 |
| Increase in IRP | 6 | 9 |
Data are presented as number (%), mean±SD, or number.
ES, Eckardt score; BMI, body mass index; DI, distensibility index; CSA, cross-sectional area; LES, lower esophageal sphincter; IRP, integrated relaxation pressure.